Human Interleukin-12 Recombinant 90178-B from BPS Bioscience, Inc.

Description

Recombinant Interleukin-12 is a disulfide-linked heterpdimer protein consisting of 306 amino acid residue p40 subunit and a 197 amino acid residue p35 subunit, and migrates due to glycosylation as an approximately 75 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Interleukin-12 mature chain was expressed in Chinese Hamster Ovary (CHO) cells

Product Specs
ItemHuman Interleukin-12 Recombinant
CompanyBPS Bioscience, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number90178-B
Quantity10 µg
ActivityThe ED₅₀ was determined by the dose-dependent proliferation of activated human T-lymphoblasts. cells was found to be in the range of 0.1-0.2 ng/ml
FormatLyophilized from 0.2 µm filtered PBS, pH 7.5
Purity≥97% by SDS-PAGE and HPLC
Molecular Weight19 kDa
SpeciesHuman
Domain/Region/Terminus23-529
NCBI Full Gene Nameinterleukin 12B
NCBI Gene AliasesCLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
TypeCytokine/Growth Factors
Source/Expression SystemHamster

Sequence

IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS and RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS

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